Why can't new antibiotics be created to combat strains of infectious bateria ---SEE MORE---?

March 11th, 2010

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  • that are resistant to drugs that are currently available??


  • Because new strains of bacteria are becomming more resisitant a lot faster than we can make and test new meds.


  • To put a drug into the market a drug company needs to spend billions for it to go through clinical trials. If a drug fails, then the drug company loses that money. Infections are a serious problem but there are already many reagents out there that is good enough to handle the majority of the strains, therefore, if a drug company wants to invest in a new drug, it will have to out do all the drugs out there.

    Best example are anti-platlets. The one that works fairly well is aspirin. Aspirin sells for 5 cents/pill and it works damn well. If your going to come out with a new drug into the market then you will have to do better than aspirin and sell it for ~2 dollars a pill just to make profit. Same with antibiotics.

    Researching for anti-biotics is not profitable because rarely are resistant infectious strains being treated however there are still some drug companies taking the risk. Think about it, there are so many other dieseases to research for such as heart diesease or cancer where the majority of the population is dying from. If you had a billion dollars to throw away, what would it be in?

    The most difficult thing about resistant strains is that either the drug can't penetrate into the bacterial membrane or if it does, it gets pumped back out my proteins known as P glycoproteins.


  • New antibiotics are under development all the time, and come on the market on a somewhat regular basis. But you don't want to take an antibiotic that hasn't been tested for safety and effectiveness, and doing so takes time. Bacteria, on the other hand, can develop resistance at their own rate. There's always going to be some lag time as new antibiotics are developed, and that time is measured in years.







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